加载中…
Anti-CD79B Antibody (Polatuzumab Biosimilar) is a research-use biosimilar antibody expressed in HEK293. The source page specifies target CD79B, reactivity Human, isotype Human IgG1-Kappa, source-listed application ELISA.
CD79B (also known as B29, Ig beta and B cell antigen receptor complex-associated protein beta-chain) is a 36-40 kDa member of the Ig-Superfamily. It is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.
