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Expression platforms

Expression platforms

Compare HEK293, CHO, E. coli, yeast and insect-cell systems, then align the route to molecular features, modification needs, project scale and downstream use.

Discuss an expression route
Multi-system
Scientific fit
Goal-led
Expert support

Platform capability atlas

Compare the host before choosing the route

The final route is confirmed after sequence and project-scope review.

HEK293

Molecule fit
Secreted proteins, antibodies, Fc fusions and complex mammalian proteins
Typical applications
Research reagents, functional validation and structural studies

CHO

Molecule fit
Antibodies, Fc fusions and glycosylation-sensitive candidates
Typical applications
Antibody research, function and process-feasibility evaluation

E. coli

Molecule fit
Non-glycosylated proteins, intracellular domains, small antigens and enzymes
Typical applications
Antigen preparation, enzyme studies and early expression screening

Yeast

Molecule fit
Secreted proteins, enzymes and recombinant proteins compatible with yeast
Typical applications
Secreted expression, enzyme production and route comparison

Insect cells

Molecule fit
Complex eukaryotic proteins, multisubunit complexes and selected membrane constructs
Typical applications
Complex proteins, structural studies and multicomponent expression

Project path

From sequence assessment to quality analysis

Get a route recommendation
  1. 01

    Sequence assessment

    Review sequence features, domains and potential risks.

  2. 02

    Platform selection

    Match the host and vector route to the molecule and study goal.

  3. 03

    Pilot expression

    Evaluate expression behavior and the next development step.

  4. 04

    Purification strategy

    Design around tags, solubility and intended downstream use.

  5. 05

    Quality analysis

    Combine purity, integrity and functional analysis as required.

  6. 06

    Delivery & support

    Deliver samples, project records and follow-up support.