Human FSTL3 Protein

Name: Human FSTL3 Protein
Brand: 普维拓生物
SKU: PR635101

货号PR635101

核心优势

高纯度

表达宿主 / 体系: HEK293
种属 (Species): Human
标签: —
纯度 (Purity): > 95% as determined by Bis-Tris PAGE > 90% as determined by HPLC
活性 / 数据: 详询活性数据

代表性质控图

技术参数

种属 (Species)

Human

分子别名 (Synonym)

FLRG; FLRGFSRP; Follistatin-like 3; FSTL3

来源/表达系统 (Source)

Recombinant Human FSTL3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Met27-Val263 [Accession | O95633-1].

分子量

The protein has a predicted MW of 26.1 kDa. Due to glycosylation, the protein migrates to 35-40 kDa based on Bis-Tris PAGE result.

内毒素 (Endotoxin)

Less than 1 EU per μg by the LAL method.

纯度 (Purity)

> 95% as determined by Bis-Tris PAGE > 90% as determined by HPLC

制剂 (Formulation)

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

重构方法 (Reconstitution)

Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.

存储 (Storage)

-20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

文献引用

(1) Kralisch S, Hoffmann A, Klöting N, Bachmann A, Kratzsch J, Stolzenburg JU, Dietel A, Beige J, Anders M, Bast I, Blüher M, Zhang MZ, Harris RC, Stumvoll M, Fasshauer M, Ebert T. FSTL3 is increased in renal dysfunction. Nephrol Dial Transplant. 2017 Oct 1;32(10):1637-1644. doi: 10.1093/ndt/gfw472 PMID: 28339962.

背景介绍

Follistatin-like 3 (FSTL3) is a novel cytokine that regulates insulin sensitivity and counteracts activin/myostatin signalling. In the present study, regulation of FSTL3 in renal dysfunction was investigated in both human chronic kidney disease (CKD) and acute kidney dysfunction (AKD). Furthermore, mFSTL3 expression was analysed in insulin-sensitive tissues in a mouse model of CKD.

FOLR1-PH1101

人FOLR1蛋白

Human FSTL3 Protein

技术参数

文献引用

背景介绍

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Human FSTL3 Protein

技术参数

文献引用

背景介绍

相关产品

定制服务与主题入口